Reduced expression of the functionally active complement receptor for iC3b but not for C3d on an avirulent mutant of Candida albicans.

doi:10.1128/iai.58.4.909-913.1990

Back to search

Article

Reduced expression of the functionally active complement receptor for iC3b but not for C3d on an avirulent mutant of Candida albicans.

Infection and immunity - 1 Apr 1990

Ollert M W, Wadsworth E, Calderone R A

Abstract excerpt

Pseudohyphae of Candida albicans bear surface receptors for iC3b and C3d. In order to determine a possible role for these receptors in the pathogenesis of candidiasis, a spontaneous C. albicans mutant, m-10, which exhibits reduced ability to adhere in vitro to fibrin platelet clots and epithelial...

Topics

Antigens, Differentiation, B-Lymphocyte
Candida albicans
Complement C3b
Complement C3d
Immunoblotting
Mutation
Receptors, Complement
Receptors, Complement 3b
Receptors, Complement 3d
Virulence

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.