Article
Fine mapping of Xq11.1-q21.33 and mutation screening of RPS6KA6, ZNF711, ACSL4, DLG3, and IL1RAPL2 for autism spectrum disorders (ASD).
Autism research : official journal of the International Society for Autism Research - 1 Jun 2011
Kantojärvi Katri, Kotala Ilona, Rehnström Karola, Ylisaukko-Oja Tero, Vanhala Raija, von Wendt Taina Nieminen, von Wendt Lennart, Järvelä Irma
Abstract excerpt
About 80% of cases with autism express intellectual disability. Both in autism and in mental retardation without autism the majority of the cases are males, suggesting a X-chromosomal effect. In fact, some molecular evidence has been obtained for a common genetic background for autism spectrum disorders (ASD) and X-linked mental retardation (XLMR). In several genome-wide scans (GWS), evidence for linkage at...
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