Determination of the inactivating alterations in two mutant alleles of the Neurospora crassa cross-pathway control gene cpc-1.

doi:10.1093/genetics/124.3.599

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Determination of the inactivating alterations in two mutant alleles of the Neurospora crassa cross-pathway control gene cpc-1.

Genetics - 1 Mar 1990

Paluh J L, Plamann M, Krüger D, Barthelmess I B, Yanofsky C, Perkins D D

Abstract excerpt

cpc-1 is the locus specifying what is believed to be the major trans-activating transcription factor that regulates expression of amino acid biosynthetic genes subject to cross-pathway control in Neurospora crassa. Mutants altered at this locus are incapable of the global increase in gene express...

Topics

Alleles
Base Sequence
Blotting, Northern
Blotting, Southern
Crosses, Genetic
Gene Rearrangement
Genes, Fungal
Genes, Regulator
Molecular Sequence Data
Mutation
Neurospora
Neurospora crassa
Polymerase Chain Reaction
Protein Biosynthesis
Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 2138111
DOI: 10.1093/genetics/124.3.599
PMCID: PMC1203953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2138111-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Nucleic Acid

Trans-Activators