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Article

Determination of the inactivating alterations in two mutant alleles of the Neurospora crassa cross-pathway control gene cpc-1.

Genetics - 1 Mar 1990

Paluh J L, Plamann M, Krüger D, Barthelmess I B, Yanofsky C, Perkins D D

Abstract excerpt

cpc-1 is the locus specifying what is believed to be the major trans-activating transcription factor that regulates expression of amino acid biosynthetic genes subject to cross-pathway control in Neurospora crassa. Mutants altered at this locus are incapable of the global increase in gene expression normally seen in response to amino acid starvation. Using polymerase chain reaction methodology we have cloned and...

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Identifiers

PMID: 2138111
DOI: 10.1093/genetics/124.3.599
PMCID: PMC1203953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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