Article
A case of mast cell leukaemia with exon 9 KIT mutation and good response to imatinib.
European journal of haematology - 1 Jun 2011
Mital Andrzej, Piskorz Anna, Lewandowski Krzysztof, Wasąg Bartosz, Limon Janusz, Hellmann Andrzej
Abstract excerpt
BACKGROUND: Mastocytosis is a myeloproliferative neoplasm characterized by the excessive proliferation of mast cells. Mast cell leukaemia (MCL), the aggressive form of this disease, requires cytoreductive therapy, such as cladribine, interferon-alpha-2b and, most recently, tyrosine kinase inhibitors - dasatinib or imatinib. PATIENT AND METHODS: We present a case of a 56-yr-old female patient with aleukaemic MCL...
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