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A method for the determination of genetic sex in the fathead minnow, Pimephales promelas, to support testing of endocrine-active chemicals.

Environmental science & technology - 1 Apr 2011

Olmstead Allen W, Villeneuve Daniel L, Ankley Gerald T, Cavallin Jenna E, Lindberg-Livingston Annelie, Wehmas Leah C, Degitz Sigmund J

Abstract excerpt

Certain endocrine-active toxicants have been reported to completely sex reverse both male and female individuals in amphibian, avian, fish, invertebrate, and reptile species, resulting in a phenotype indistinguishable from unaffected individuals. Detection of low-level sex reversal often requires large numbers of organisms to achieve the necessary statistical power, especially in those species with predominantly...

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PMID: 21361318
DOI: 10.1021/es103327r

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