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Article

Malate synthase expression is deregulated in the Pseudomonas aeruginosa cystic fibrosis isolate FRD1.

Canadian journal of microbiology - 1 Mar 2011

Hagins Jessica M, Scoffield Jessica, Suh Sang-Jin, Silo-Suh Laura

Abstract excerpt

Pseudomonas aeruginosa causes chronic pulmonary infections, which can persist for decades, in patients with cystic fibrosis (CF). Current evidence suggests that the glyoxylate pathway is an important metabolic pathway for P. aeruginosa growing within the CF lung. In this study, we identified glcB, which encodes for the second key enzyme of the glyoxylate pathway, malate synthase, as a requirement for virulence of...

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PMID: 21358759
DOI: 10.1139/W10-118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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