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Cytomegalovirus UL103 Controls Virion and Dense Body Egress

24 Feb 2011

Abstract excerpt

Human cytomegalovirus UL103 encodes a tegument protein that is conserved across herpesvirus subgroups. Mutant viruses lacking this gene product exhibit dramatically reduced accumulation of cell-free virus progeny and poor cell-to-cell spread. Given that viral proteins and viral DNA accumulate with normal kinetics in cells infected with mutant virus, UL103 appears to function during the late phase of replication,...

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PMID: 21345947
DOI: 10.1128/jvi.01682-10

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