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Engineering a stem cell house into a home

31 Jan 2011

Abstract excerpt

In the body, tissue homeostasis is established and maintained by resident tissue-specific adult stem cells (aSCs). Through preservation of bidirectional communications with the surrounding niche and integration of biophysical and biochemical cues, aSCs actively direct the regeneration of aged, injured and diseased tissues. Currently, the ability to guide the behavior and fate of aSCs in the body or in culture...

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PMID: 21345268
DOI: 10.1186/scrt44

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