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Article

MicroRNAs: a potential interface between the circadian clock and human health

1 Jan 2011

Abstract excerpt

The biochemical activity of a stunning diversity of cell types and organ systems is shaped by a 24-hour (circadian) clock. This rhythmic drive to a good deal of the transcriptome (up to 15% of all coding genes) imparts circadian modulation over a wide range of physiological and behavioral processes (from cell division to cognition). Further, dysregulation of the clock has been implicated in the pathogenesis of a...

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PMID: 21345247
DOI: 10.1186/gm224

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