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Trypanosoma cruzi: parasite persistence in tissues in chronic chagasic Brazilian patients

1 Feb 2011

Abstract excerpt

Chagas disease in the chronic phase may develop into cardiac and/or digestive forms. The pathogenesis of the disease is not yet clear and studies have been carried out to elucidate the role of parasite persistence in affected organs. The aim of this study was to detect and quantify Trypanosoma cruzi in paraffin-embedded tissue samples from chronic patients using NPCR (nested polymerase chain reaction) and QPCR...

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PMID: 21340361
DOI: 10.1590/s0074-02762011000100014

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