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Article

A genetic variant near the equine interleukin 6 gene associated with copper:zinc ratio.

Veterinary journal (London, England : 1997) - 1 Nov 2011

Beghelli Daniela, Giacconi Robertina, Mocchegiani Eugenio, Cipriano Catia, Malavolta Marco, Renieri Carlo

Abstract excerpt

The aim of this study was to validate an A/T single nucleotide polymorphism (SNP) corresponding to a LINE2 sequence located ∼1.1kb downstream of the IL-6 gene (SNP BIEC2-911738) and to determine if this variant is correlated with interleukin 6 (IL-6) modulation or with different plasma concentrations of Zn, Cu, Se and Fe. The frequency of the newly described variant T ranged from 0 to 23.1% among different breeds...

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PMID: 21330167
DOI: 10.1016/j.tvjl.2010.12.028

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