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CD24: A Novel Surface Marker for PDX1-Positive Pancreatic Progenitors Derived from Human Embryonic Stem Cells

3 Feb 2011

Abstract excerpt

Human ESCs provide a promising cell resource for the treatment of type I diabetes mellitus. Although PDX1-positive pancreatic progenitors can be efficiently generated from human ESCs by stepwise induction, further in vitro differentiation into functional, mature beta cells is not efficient or reproducible. Purification of pancreatic progenitor cells could facilitate the identification of signals that regulate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21308865
DOI: 10.1002/stem.608

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