Article
The clinical features of patients with the homozygous 235delC and the compound-heterozygous Y136X/G45E of the GJB2 mutations (Connexin 26) in cochlear implant recipients.
Auris, nasus, larynx - 1 Aug 2011
Yoshikawa Satoko, Kawano Atsushi, Hayashi Chieri, Nishiyama Nobuhiro, Kawaguchi Sachie, Furuse Hiroko, Ikeda Katsuhisa, Suzuki Mamoru, Nakagawa Masahumi
Abstract excerpt
OBJECTIVE: This study aimed to investigate the prevalence of GJB2 gene for the 235delC mutations, the clinical features and the outcomes of patients who had undergone cochlear implantation. METHODS: We have sequenced the coding region of GJB2 gene for 135 patients with sensorineural deaf from September 2000 to May 2009. Of the 135 patients, the patients with the homozygous 235delC and the compound-heterozygous...
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