Article
Next-generation sequencing of Coccidioides immitis isolated during cluster investigation.
Emerging infectious diseases - 1 Feb 2011
Engelthaler David M, Chiller Tom, Schupp James A, Colvin Joshua, Beckstrom-Sternberg Stephen M, Driebe Elizabeth M, Moses Tracy, Tembe Waibhav, Sinari Shripad, Beckstrom-Sternberg James S, Christoforides Alexis, Pearson John V, Carpten John, Keim Paul, Peterson Ashley, Terashita Dawn, Balajee S Arunmozhi
Abstract excerpt
Next-generation sequencing enables use of whole-genome sequence typing (WGST) as a viable and discriminatory tool for genotyping and molecular epidemiologic analysis. We used WGST to confirm the linkage of a cluster of Coccidioides immitis isolates from 3 patients who received organ transplants from a single donor who later had positive test results for coccidioidomycosis. Isolates from the 3 patients were nearly...
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