Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-K12-7-5p Encoded by Kaposi's Sarcoma-Associated Herpesvirus Stabilizes the Latent State by Targeting Viral ORF50/RTA

20 Jan 2011

Abstract excerpt

Seventeen miRNAs encoded by Kaposi's sarcoma-associated herpesvirus (KSHV) have been identified and their functions have begun to be characterized. Among these miRNAs, we report here that miR-K12-7 directly targets the replication and transcription activator (RTA) encoded by open reading frame 50. We found that miR-K12-7 targeted the RTA 3' untranslated region (RTA3'UTR) in a seed sequence-dependent manner....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21283761
DOI: 10.1371/journal.pone.0016224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-K12-7-5p Encoded by Kaposi's Sarcoma-Associated Herpesvirus Stabilizes the Latent State by Targeting Viral ORF50/RTAPMID 21283761Read ↗

Reactivation and Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus: An UpdateSemantic proximity Read ↗

Towards Better Understanding of KSHV Life Cycle: from Transcription and Posttranscriptional Regulations to PathogenesisSemantic proximity Read ↗

Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signalingSemantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cellsSemantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cellsSemantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus Transactivator RTA Promotes Degradation of the Repressors To Regulate Viral Lytic ReplicationSemantic proximity Read ↗

Comparative Study of Regulation of RTA-Responsive Genes in Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8Semantic proximity Read ↗

Cloning and Identification of a MicroRNA Cluster within the Latency-Associated Region of Kaposi's Sarcoma-Associated HerpesvirusSemantic proximity Read ↗

Small RNA profiling reveals antisense transcription throughout the KSHV genome and novel small RNAsSemantic proximity Read ↗

A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirusSemantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) replication and transcription factor activates the K9 (vIRF) gene through two distinct cis elements by a non-DNA-binding mechanism.Semantic proximity Read ↗

K-bZIP of Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 (KSHV/HHV-8) Binds KSHV/HHV-8 Rta and Represses Rta-Mediated TransactivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.