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Article

Desmin mutations in the terminal consensus motif prevent synemin-desmin heteropolymer filament assembly.

Experimental cell research - 1 Apr 2011

Chourbagi Oussama, Bruston Francine, Carinci Marianna, Xue Zhigang, Vicart Patrick, Paulin Denise, Agbulut Onnik

Abstract excerpt

Disorganization of the desmin network is associated with cardiac and skeletal myopathies characterized by accumulation of desmin-containing aggregates in the cells. Multiple associations of intermediate filament proteins form a network to increase mechanical and functional stability. Synemin is a desmin-associated type VI intermediate filament protein. Neither its impact on desmin network nor how it integrates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21262226
DOI: 10.1016/j.yexcr.2011.01.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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