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Article

Reported early family environment covaries with menarcheal age as a function of polymorphic variation in estrogen receptor-α.

Development and psychopathology - 1 Feb 2011

Manuck Stephen B, Craig Anna E, Flory Janine D, Halder Indrani, Ferrell Robert E

Abstract excerpt

Age at menarche, a sentinel index of pubertal maturation, was examined in relation to early family relationships (conflict, cohesion) and polymorphic variation in the gene encoding estrogen receptor-α (ESR1) in a midlife sample of 455 European American women. Consistent with prior literature, women who reported being raised in families characterized by close interpersonal relationships and little conflict tended...

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Source

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Identifiers

PMID: 21262040
DOI: 10.1017/S0954579410000659
PMCID: PMC3077552

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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