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[Molecular combing in studies of the genome organization and DNA replication].

Genetika - 1 Oct 2010

Kolesnikova T D, Demakov S A, Ivankin A V, Zhimulev I F

Abstract excerpt

Molecular combing (MC) yields preparations where individual DNA molecules are uniformly stretched and are parallel to each other. Fluorescence in situ hybridization on such preparations allows an exact mapping of DNA sequences, and pulsed inclusion of halogenated deoxyuridine analogs and their detection using fluorochrome-conjugated antibodies makes it possible to visualize replication. The MC technique was...

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PMID: 21254567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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