Article
Single nucleotide polymorphism of CACNA2D1 gene and its association with milk somatic cell score in cattle.
Molecular biology reports - 1 Nov 2011
Yuan Zheng Rong, Li Jiao, Liu Li, Zhang Lu Pei, Zhang Li Min, Chen Cui, Chen Xiao Jie, Gao Xue, Li Jun Ya, Chen Jin Bao, Gao Hui Jiang, Xu Shang Zhong
Abstract excerpt
The objective of the present study was to identify polymorphisms of the CACNA2D1 gene, and to analyze associations between these polymorphisms and mastitis in several cattle breeds. Through PCR-RFLP methods and DNA sequencing, an allelic variant corresponding to the A→G mutations and Aspartic (Asp) to Glycine (Gly) amino acid replacement at positions 526745 in the exon 25 of bovine CACNA2D1 gene could be...
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