Article
Extranuclear protection of chromosomal DNA from oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America - 25 Jan 2011
Vanderauwera Sandy, Suzuki Nobuhiro, Miller Gad, van de Cotte Brigitte, Morsa Stijn, Ravanat Jean-Luc, Hegie Alicia, Triantaphylidès Christian, Shulaev Vladimir, Van Montagu Marc C E, Van Breusegem Frank, Mittler Ron
Abstract excerpt
Eukaryotic organisms evolved under aerobic conditions subjecting nuclear DNA to damage provoked by reactive oxygen species (ROS). Although ROS are thought to be a major cause of DNA damage, little is known about the molecular mechanisms protecting nuclear DNA from oxidative stress. Here we show that protection of nuclear DNA in plants requires a coordinated function of ROS-scavenging pathways residing in the...
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