Article
Comparative evaluation of the performance of the Abbott RealTime HIV-1 assay for measurement of HIV-1 plasma viral load on genetically diverse samples from Greece.
Virology journal - 11 Jan 2011
Katsoulidou Antigoni, Rokka Chrysoula, Issaris Catherine, Haida Catherine, Tzannis Kimon, Sypsa Vana, Detsika Maria, Paraskevis Dimitrios, Hatzakis Angelos
Abstract excerpt
BACKGROUND: HIV-1 is characterized by increased genetic heterogeneity which tends to hinder the reliability of detection and accuracy of HIV-1 RNA quantitation assays. METHODS: In this study, the Abbott RealTime HIV-1 (Abbott RealTime) assay was compared to the Roche Cobas TaqMan HIV-1 (Cobas TaqMan) and the Siemens Versant HIV-1 RNA 3.0 (bDNA 3.0) assays, using clinical samples of various viral load levels and...
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