Article
Spurious polyadenylation of Norovirus Narita 104 capsid protein mRNA in transgenic plants.
Plant molecular biology - 1 Feb 2011
Mathew Lolita G, Maloney Bryan, Takeda Naokazu, Mason Hugh S
Abstract excerpt
Noroviruses are members of the family Caliciviridae, and cause a highly communicable gastroenteritis in humans. We explored the potential to develop a plant-based vaccine against Narita 104 virus, a Genogroup II Norovirus. In stably transgenic potato, we obtained very poor expression of Narita 104 virus capsid protein (NaVCP) despite the use of a strong constitutive promoter (dual enhancer 35S) driving the native...
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