Article
[Pendrin: its role in kidney function and hypertension].
Medecine sciences : M/S - 1 Dec 2010
Doucet Alain, Eladari Dominique
Abstract excerpt
Loss-of-function mutations of the pendrin gene are responsible for a pathology characterized by dysfunctions of thyroid and inner ear. However, it rapidly appeared after its discovery that the anion exchanger encoded by this gene plays a central role in kidneys. This brief review pictures the evolution of our knowledge regarding renal functions of pendrin, with a special emphasis to its recently identified roles...
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