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Article

Gene defects in the soma: some get it and some don't!

The Journal of clinical investigation - 1 Jan 2011

Lo Bernice, Lenardo Michael J

Abstract excerpt

Advances in DNA sequencing technologies have increased attention on genetic variation in somatic tissues. Although long known to cause neoplastic diseases, somatic variation is now being investigated as a pathogenetic mechanism for other diseases. Somatic changes are genomic DNA variations that were not inherited but arise in tissues throughout life. In this issue of the JCI, Magerus-Chatinet et al. explore...

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Identifiers

PMID: 21183786
DOI: 10.1172/JCI45664
PMCID: PMC3007168

Genes

FAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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