Article
The Genomic HyperBrowser: inferential genomics at the sequence level.
Genome biology - 1 Jan 2010
Sandve Geir K, Gundersen Sveinung, Rydbeck Halfdan, Glad Ingrid K, Holden Lars, Holden Marit, Liestøl Knut, Clancy Trevor, Ferkingstad Egil, Johansen Morten, Nygaard Vegard, Tøstesen Eivind, Frigessi Arnoldo, Hovig Eivind
Abstract excerpt
The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical analysis of sequence-level genomic information. We provide a growing collection of generic biological investigations that query pairwise relations between tracks, represented as...
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