Hobotnica: exploring molecular signature quality.

doi:10.12688/f1000research.74846.2

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Article

Hobotnica: exploring molecular signature quality.

F1000Research - 1 Jan 2021

Stupnikov Alexey, Sizykh Alexey, Budkina Anna, Favorov Alexander, Afsari Bahman, Wheelan Sarah, Marchionni Luigi, Medvedeva Yulia

Abstract excerpt

A Molecular Features Set (MFS), is a result of a vast diversity of bioinformatics pipelines. The lack of a "gold standard" for most experimental data modalities makes it difficult to provide valid estimation for a particular MFS's quality. Yet, this goal can partially be achieved by analyzing inner-sample Distance Matrices (DM) and their power to distinguish between phenotypes. The quality of a DM can be assessed...

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PMID: 36204675
DOI: 10.12688/f1000research.74846.2
PMCID: PMC9513410.2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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