Article
First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response.
Neuro-oncology - 1 Feb 2011
Taal Walter, Dubbink Hendrikus J, Zonnenberg Chris B L, Zonnenberg Bernard A, Postma Tjeerd J, Gijtenbeek Johanna M M, Boogerd Willem, Groenendijk Floris H, Kros Johan M, Kouwenhoven Mathilde C M, van Marion Ronald, van Heuvel Irene, van der Holt Bronno, Bromberg Jacoline E C, Sillevis Smitt Peter A E, Dinjens Winand N M, van den Bent Martin J
Abstract excerpt
Only a few studies examined the effect of temozolomide (TMZ) in recurrent low-grade astrocytoma (LGA) after surgery, none of which included a homogeneous and sufficiently sized group of patients with progression after radiotherapy (RT). We evaluated a cohort of 58 patients treated with TMZ for pr...
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