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Real‐time polymerase chain reaction detection of parvovirus B19 DNA in blood donations using a commercial and an in‐house assay

22 Dec 2010

Abstract excerpt

BACKGROUND: European regulations require testing of manufacturing plasma for parvovirus B19 (B19) DNA to limit the load of this virus to a maximum acceptable level of 10 IU/µL. To meet this requirement, most manufacturers introduced a test algorithm to identify and eliminate high-load donations before making large manufacturing pools of plasma units. Sanquin screens all donations using a commercial assay from...

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PMID: 21175647
DOI: 10.1111/j.1537-2995.2010.02995.x

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