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Article

The Role of Osteoclast-Associated Receptor in Osteoimmunology

20 Dec 2010

Abstract excerpt

The term osteoimmunology is coined for molecular and cellular cross talk between the skeletal and immune system. Immunomodulatory signals have long been implicated as key regulators of bone metabolism. Recently, osteoclast-associated receptor (OSCAR), an IgG-like receptor, has been identified as an important osteoimmunological mediator. OSCAR expression in bone is highly conserved across different species, and...

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PMID: 21172874
DOI: 10.4049/jimmunol.1002483

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