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Article

Prognostic Biomarkers for Esophageal Adenocarcinoma Identified by Analysis of Tumor Transcriptome

30 Nov 2010

Abstract excerpt

BACKGROUND: Despite many attempts to establish pre-treatment prognostic markers to understand the clinical biology of esophageal adenocarcinoma (EAC), validated clinical biomarkers or parameters remain elusive. We generated and analyzed tumor transcriptome to develop a practical biomarker prognostic signature in EAC. METHODOLOGY/PRINCIPAL FINDINGS: Untreated esophageal endoscopic biopsy specimens were obtained...

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PMID: 21152079
DOI: 10.1371/journal.pone.0015074

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