Article
Vessel tortuousity and reduced vascularization in the fetoplacental arterial tree after maternal exposure to polycyclic aromatic hydrocarbons.
American journal of physiology. Heart and circulatory physiology - 1 Feb 2011
Rennie Monique Y, Detmar Jacqui, Whiteley Kathie J, Yang Jian, Jurisicova Andrea, Adamson S Lee, Sled John G
Abstract excerpt
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants and the main toxicants found in cigarettes. Women are often exposed to PAHs before pregnancy, typically via prepregnancy smoking. To determine how prepregnancy exposure affects the fetoplacental vasculature of the placenta, we exposed female mice to PAHs before conception, perfused the fetoplacental arterial trees with X-ray contrast...
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