Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study.

European journal of endocrinology - 1 Mar 2011

Cheung Chloe Y Y, Tso Annette W K, Cheung Bernard M Y, Xu Aimin, Ong K L, Law Lawrence S C, Wat Nelson M S, Janus Edward D, Sham Pak C, Lam Karen S L

Abstract excerpt

OBJECTIVE: Central obesity predisposes to various cardiometabolic diseases and is a key component of the metabolic syndrome (MetS). We have previously demonstrated that three obesity-susceptible single nucleotide polymorphisms (SNPs), rs10938397 (GNPDA2), rs8050136 (FTO) and rs17782313 (MC4R), were associated with obesity and waist circumference in cross-sectional studies in the Chinese population. In this study,...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to FTO gene
Share to Genetic Variation
Share to Genotype
Share to Longitudinal Studies
Share to Metabolic Syndrome
Share to Obesity
Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 21147891
DOI: 10.1530/EJE-10-0902

Genes

GNPDA2
FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study.PMID 21147891Read ↗

Genetic markers and continuity of healthy metabolic status: Tehran cardio-metabolic genetic study (TCGS).Semantic proximity Read ↗

Genetic association study with metabolic syndrome and metabolic-related traits in a cross-sectional sample and a 10-year longitudinal sample of chinese elderly population.Semantic proximity Read ↗

Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a chinese population.Semantic proximity Read ↗

An obesity genetic risk score is associated with metabolic syndrome in Chinese children.Semantic proximity Read ↗

New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.Semantic proximity Read ↗

Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children.Semantic proximity Read ↗

The joint effect of PPARG upstream genetic variation in association with long-term persistent obesity: Tehran cardio-metabolic genetic study (TCGS).Semantic proximity Read ↗

Identification of three genetic variants as novel susceptibility loci for body mass index in a Japanese population.Semantic proximity Read ↗

Association of GCKR Gene Polymorphisms with Metabolic Syndrome in a Han Population from Northeast China.Semantic proximity Read ↗

Association between genetic variants in metabolic syndrome-related genes and risk of obstructive sleep apnea among a Chinese populationSemantic proximity Read ↗

Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients.Semantic proximity Read ↗

A genetic variation in the fat mass- and obesity-associated gene is associated with obesity and newly diagnosed type 2 diabetes in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.