Article
Maternal and fetal PROGINS progesterone receptor polymorphism reduces the risk for transient tachypnea of the newborn.
Clinical laboratory - 1 Jan 2010
Alter Markus, Pfab Thiemo, Guthmann Florian, Burdack Aline, Kempiners Nina, Kalk Philipp, Chen You-Peng, Hocher Berthold
Abstract excerpt
BACKGROUND: Transient tachypnea of the newborn (TTN) is the most common perinatal respiratory disorder. It was suggested that the pathogenesis of TTN might involve altered activity of female sex hormones. This study analyzed whether the PROGINS progesterone receptor polymorphism, which is less responsive to progesterone, is associated with TTN. METHODS: A cohort of 2352 infants born to Caucasian women at the...
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