Article
Hypermethylation of CpG islands and shores around specific microRNAs and mirtrons is associated with the phenotype and presence of bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2011
Dudziec Ewa, Miah Saiful, Choudhry Hani M Z, Owen Helen C, Blizard Sheila, Glover Maggie, Hamdy Freddie C, Catto James W F
Abstract excerpt
PURPOSE: To analyze the role and translational potential for hypermethylation of CpG islands and shores in the regulation of small RNAs within urothelial cell carcinoma (UCC). To examine microRNAs (miR) and mirtrons, a new class of RNA located within gene introns and processed in a Drosha-indepen...
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