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Article

Detection of genetic hypopituitarism in an adult population of idiopathic pituitary insufficiency patients with growth hormone deficiency.

Pituitary - 1 Sept 2011

Nyström Helena Filipsson, Saveanu Alexandru, Barbosa Edna J L, Barlier Anne, Enjalbert Alain, Glad Camilla, Palming Jenny, Johannsson Gudmundur, Brue Thierry

Abstract excerpt

Idiopathic pituitary insufficiency (IPI) is diagnosed in 10% of all hypopituitary patients. There are several known and unknown aetiologies within the IPI group. The aim of this study was to investigate an adult IPI population for genetic cause according a screening schedule. From files of 373 GH deficient (GHD) patients on GH replacement 50 cases with IPI were identified. Of the 39 patients that approved to the...

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Source

Identifiers

PMID: 21132537
DOI: 10.1007/s11102-010-0278-8

Genes

PROP1
HESX1
LHX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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