Article
ICF syndrome in Saudi Arabia: immunological, cytogenetic and molecular analysis.
Journal of clinical immunology - 1 Apr 2011
Kaya Namik, Al-Muhsen Saleh, Al-Saud Bandar, Al-Bakheet Albandary, Colak Dilek, Al-Ghonaium Abdulaziz, Al-Dhekri Hasan, Al-Mousa Hamoud, Arnaout Rand, Al-Owain Mohammad, Iqbal Mohammad
Abstract excerpt
BACKGROUND: Immunodeficiency, centromeric instability and facial anomalies (ICF) syndrome is an extremely rare autosomal recessive disorder. In addition to the juxtacentromeric heterochromatic instability, the disease is characterized by variable reduction in serum immunoglobulin levels which cause most ICF patients to succumb to infectious diseases before adulthood as well as exhibit facial dysmorphism including...
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