Article
Geftinib.
Journal of cancer research and therapeutics - 1 Jan 2000
Gupta Ajay, Raina Vinod
Abstract excerpt
Gefitinib is an orally active, highly selective, reversible inhibitor of the tyrosine kinase domain associated with the epidermal growth factor receptor (EGFR). EGFR gene mutations, never smoking status, Asian origin and adenocarcinoma histology are associated with good clinical responses to geftinib. Geftinib has generally been tried in the setting of chemotherapy refractory disease in patients who have failed...
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