Article
Screening of 38 genes identifies mutations in 62% of families with nonsyndromic deafness in Turkey.
Genetic testing and molecular biomarkers - 1 Jan 2000
Duman Duygu, Sirmaci Asli, Cengiz F Basak, Ozdag Hilal, Tekin Mustafa
Abstract excerpt
More than 60% of prelingual deafness is genetic in origin, and of these up to 95% are monogenic autosomal recessive traits. Causal mutations have been identified in 1 of 38 different genes in a subset of patients with nonsyndromic autosomal recessive deafness. In this study, we screened 49 unrelated Turkish families with at least three affected children born to consanguineous parents. Probands from all families...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.