Article
Upregulation of connexin 30 in intestinal phenotype gastric cancer and its reduction during tumor progression.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2010
Sentani Kazuhiro, Oue Naohide, Sakamoto Naoya, Anami Katsuhiro, Naito Yutaka, Aoyagi Kazuhiko, Sasaki Hiroki, Yasui Wataru
Abstract excerpt
AIMS: The mucin phenotype is associated with clinicopathological findings and tumorigenesis in gastric cancer (GC). The aim was to search for a novel marker regulating the intestinal phenotype of GC. METHODS AND RESULTS: We performed microarray analyses, and GJB6 (encoding connexin 30) was identified as a gene associated with the intestinal phenotype. Immunostaining of connexin 30 in 169 GC cases revealed that 47...
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