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Genetics and genomics of human ageing

29 Nov 2010

Abstract excerpt

Ageing in humans is typified by the decline of physiological functions in various organs and tissues leading to an increased probability of death. Some individuals delay, escape or survive much of this age-related decline and live past age 100. Studies comparing centenarians to average-aged individuals have found polymorphisms in genes that are associated with long life, including APOE and FOXOA3, which have been...

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PMID: 21115529
DOI: 10.1098/rstb.2010.0259

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