Article
Gene-environment interactions in the pre-Industrial Era: the cancer of King Ferrante I of Aragon (1431-1494).
Human pathology - 1 Mar 2011
Ottini Laura, Falchetti Mario, Marinozzi Silvia, Angeletti Luciana Rita, Fornaciari Gino
Abstract excerpt
King Ferrante I of Aragon, leading figure of the Italian Renaissance, died in 1494. The autopsy of his mummy revealed a tumor infiltrating the small pelvis. We examined the histologic and molecular features of this ancient tumor to investigate its primary origin. Hematoxylin-eosin, Van Gieson, and Alcian Blue staining showed neoplastic cells infiltrating muscular fibers and forming pseudo-glandular lumina...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.