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Article

The role of Frizzled-4 mutations in familial exudative vitreoretinopathy and Coats disease.

The British journal of ophthalmology - 1 Apr 2011

Robitaille Johane M, Zheng Binyou, Wallace Karin, Beis M Jill, Tatlidil Cuneyt, Yang Jenny, Sheidow Tom G, Siebert Lee, Levin Alex V, Lam Wai-Ching, Arthur Brian W, Lyons Christopher J, Jaakkola Elisa, Tsilou Ekaterini, Williams Charles A, Weaver Richard Grey, Shields Carol L, Guernsey Duane L

Abstract excerpt

AIM: The aim of this study is to assess the role of Frizzled-4 (FZD4) in familial exudative vitreoretinopathy (FEVR) and Coats disease. METHODS: Tissue samples were collected for DNA extraction and automated DNA sequencing of the two coding exons of FZD4 in both directions. Cases carrying a FZD4...

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Source

Identifiers

PMID: 21097938
DOI: 10.1136/bjo.2010.190116

Genes

FZD4
LRP5
NDP
TSPAN12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21097938-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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