Article
Arabidopsis type I metacaspases control cell death.
Science (New York, N.Y.) - 3 Dec 2010
Coll Nuria S, Vercammen Dominique, Smidler Andrea, Clover Charles, Van Breusegem Frank, Dangl Jeffery L, Epple Petra
Abstract excerpt
Metacaspases are distant relatives of animal caspases found in protozoa, fungi, and plants. Limited experimental data exist defining their function(s), despite their discovery by homology modeling a decade ago. We demonstrated that two type I metacaspases, AtMC1 and AtMC2, antagonistically control programmed cell death in Arabidopsis. AtMC1 is a positive regulator of cell death and requires conserved caspase-like...
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