Article
Gender differences in the effects of peroxisome proliferator-activated receptor γ2 gene polymorphisms on metabolic adversity in patients with schizophrenia or schizoaffective disorder.
Progress in neuro-psychopharmacology & biological psychiatry - 15 Jan 2011
Chen Chun-Hsin, Lu Mong-Liang, Kuo Po-Hsiu, Chen Po-Yu, Chiu Chih-Chiang, Kao Chung-Feng, Huang Ming-Chyi
Abstract excerpt
OBJECTIVE: Metabolic syndrome (MS) is a major health problem in schizophrenic patients. Peroxisome proliferator-activated receptor γ2 (PPARγ2) is one of the candidate genes responsible for the liability to metabolic problems. In this study, we investigated the effect of the PPARγ2 gene Pro12Ala and C161T polymorphisms on metabolic adversities in patients with schizophrenia or schizoaffective disorder. METHODS:...
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