Article
Refractory periodontitis population characterized by a hyperactive oral neutrophil phenotype.
Journal of periodontology - 1 May 2011
Aboodi Guy M, Goldberg Michael B, Glogauer Michael
Abstract excerpt
BACKGROUND: Neutrophils, in addition to being the primary protective component of the innate immune system, also contribute to periodontal destruction through production of reactive oxygen species (ROS), which cause damage to connective tissues and extracellular matrix after neutrophil activation. We have previously shown that hyperactive neutrophils are present in peripheral blood samples of patients diagnosed...
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