Article
Effect of ADRA2A and BDNF gene-gene interaction on the continuous performance test phenotype.
Psychiatric genetics - 1 Jun 2011
Cho Soo-Churl, Kim Jae-Won, Kim Hyo-Won, Kim Boong-Nyun, Shin Min-Sup, Cho Dae-Yeon, Jung Sun-Woo, Chung Un-Sun, Son Jung-Woo
Abstract excerpt
Complex phenotypes such as performance on the continuous performance test (CPT) are likely to exhibit epistasis. Genetic polymorphisms of noradrenergic system and brain-derived neurotrophic factor (BDNF), which participates in the differentiation and survival of noradrenergic neurons, have been reported to be associated with the performance on CPT. We evaluated the effect of the adrenergic α-2A receptor (ADRA2A)...
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