Article
Association of sequence variants in CKM (creatine kinase, muscle) and COX4I2 (cytochrome c oxidase, subunit 4, isoform 2) genes with racing performance in Thoroughbred horses.
Equine veterinary journal. Supplement - 1 Nov 2010
Gu J, MacHugh D E, McGivney B A, Park S D E, Katz L M, Hill E W
Abstract excerpt
REASONS FOR PERFORMING STUDY: The wild progenitors of the domestic horse were subject to natural selection for speed and stamina for millennia. Uniquely, this process has been augmented in Thoroughbreds, which have undergone at least 3 centuries of intense artificial selection for athletic phenotypes. While the phenotypic adaptations to exercise are well described, only a small number of the underlying genetic...
Topics
- Animals
- Creatine Kinase, MM Form
- Electron Transport Complex IV
- Gene Expression Regulation
- Horses
- Polymorphism, Single Nucleotide
- Running