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Article

Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1

3 Nov 2010

Abstract excerpt

BACKGROUND: Despite extensive research, the details of the biological mechanisms by which cancer cells acquire motility and invasiveness are largely unknown. This study identifies an invasion associated gene signature shedding light on these mechanisms. METHODS: We analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression indicates the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21047417
DOI: 10.1186/1755-8794-3-51

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