Article
MCT1, MCT4 and CD147 gene polymorphisms in healthy horses and horses with myopathy.
Research in veterinary science - 1 Dec 2011
Mykkänen A K, Koho N M, Reeben M, McGowan C M, Pösö A R
Abstract excerpt
Polymorphisms in human lactate transporter proteins (monocarboxylate transporters; MCTs), especially the MCT1 isoform, can affect lactate transport activity and cause signs of exercise-induced myopathy. Muscles express MCT1, MCT4 and CD147, an ancillary protein, indispensable for the activity of MCT1 and MCT4. We sequenced the coding sequence (cDNA) of horse MCT4 for the first time and examined polymorphisms in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
