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Age‐related changes in mesenchymal stem cells derived from rhesus macaque bone marrow

22 Oct 2010

Abstract excerpt

The regeneration potential of mesenchymal stem cells (MSCs) diminishes with advanced age and this diminished potential is associated with changes in cellular functions. This study compared MSCs isolated from the bone marrow of rhesus monkeys (rBMSCs) in three age groups: young (< 5 years), middle (8-10 years), and old (> 12 years). The effects of aging on stem cell properties and indicators of stem cell fitness...

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PMID: 20969724
DOI: 10.1111/j.1474-9726.2010.00646.x

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